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Figure 1: Various histological appearances of granulomas. (A) Lobular well defined granuloma, classical intra-lobular location. (B) Dense intralobular infiltration by lymphocytes and epithelioid cells; focal epithelitis (Case 2). (C) Epithelioid cell granuloma showing numerous giant cell, lymphocytes and macrophages. (D) Necrotizing granuloma showing central neutrophilic abscess walled off by dense infiltrate of chronic inflammatory cells (Cases 4 and 6). (E) High-power view of the above necrotizing granuloma shows plasma cell rich infiltrate and a giant cell (Cases 4 and 6). (F) Loose granulomas showing edema and a large central dilated duct filled with secretions (Case 8) |
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