%A Nayyar, Abhishek %A Kartheeki, B %A Sinha, Pallavi %A Zakaria, Kazi %A Chandrakant, Channe %A Kulkarni, Abhay %T Cytomorphometric analysis of exfoliated buccal mucosal cells in smokers and tobacco chewers %9 Original Article %D 2017 %J International Journal of Histopathological Interpretation %R 10.4103/ijhi.ijhi_4_17 %P 1-4 %V 6 %N 1 %U https://www.ijhi.org/article.asp?issn=WKMP-0130;year=2017;volume=6;issue=1;spage=1;epage=4;aulast=Nayyar %8 January 1, 2017 %X Aims and Objectives: Exfoliative cytology is a minimally invasive procedure that has been used for the detection of early changes in clinically normal oral mucosa of tobacco users. This study highlights the cause-effect relationship between tobacco usage in varied forms and the structural cellular and nuclear alterations in different age groups. Materials and Methods: This study was conducted with different age groups who were tobacco users as a planned, cross-sectional study. Results: The results of the study revealed that the mean nuclear diameter (ND) and cytoplasmic diameter (CD) showed a statistically significant difference in the control group and in smokers and tobacco chewers. Conclusion: Increase in ND and decreased CD, as well as an altered nucleo-cytoplasmic ratio, appear to be due to chronic tobacco usage and cytomorphometric analysis can be used to detect these cellular and subcellular alterations at an early enough stage before actually a frank, morphological change can be appreciated in relation to the oral mucosa. %0 Journal Article %I Wolters Kluwer Medknow Publications %@ WKMP-0130