International Journal of Histopathological Interpretation

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 6  |  Issue : 1  |  Page : 1--4

Cytomorphometric analysis of exfoliated buccal mucosal cells in smokers and tobacco chewers


Abhishek Singh Nayyar1, B Kartheeki1, Pallavi Sinha1, Kazi Abdullah Zakaria2, Channe Rashmi Chandrakant2, Abhay Kulkarni2 
1 Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani, India
2 Department of Oral Medicine and Radiology, Pandit Deendayal Upadhyay Dental College and Hospital, Solapur, Maharashtra, India

Correspondence Address:
Abhishek Singh Nayyar
Department of Oral Medicine and Radiology, Saraswati Dhanwantari Dental College and Hospital, Post-Graduate Research Institute, Parbhani - 431 401, Maharashtra
India

Aims and Objectives: Exfoliative cytology is a minimally invasive procedure that has been used for the detection of early changes in clinically normal oral mucosa of tobacco users. This study highlights the cause-effect relationship between tobacco usage in varied forms and the structural cellular and nuclear alterations in different age groups. Materials and Methods: This study was conducted with different age groups who were tobacco users as a planned, cross-sectional study. Results: The results of the study revealed that the mean nuclear diameter (ND) and cytoplasmic diameter (CD) showed a statistically significant difference in the control group and in smokers and tobacco chewers. Conclusion: Increase in ND and decreased CD, as well as an altered nucleo-cytoplasmic ratio, appear to be due to chronic tobacco usage and cytomorphometric analysis can be used to detect these cellular and subcellular alterations at an early enough stage before actually a frank, morphological change can be appreciated in relation to the oral mucosa.


How to cite this article:
Nayyar AS, Kartheeki B, Sinha P, Zakaria KA, Chandrakant CR, Kulkarni A. Cytomorphometric analysis of exfoliated buccal mucosal cells in smokers and tobacco chewers.Int J Histopathol Interpret 2017;6:1-4


How to cite this URL:
Nayyar AS, Kartheeki B, Sinha P, Zakaria KA, Chandrakant CR, Kulkarni A. Cytomorphometric analysis of exfoliated buccal mucosal cells in smokers and tobacco chewers. Int J Histopathol Interpret [serial online] 2017 [cited 2020 Apr 6 ];6:1-4
Available from: http://www.ijhi.org/article.asp?issn=WKMP-0130;year=2017;volume=6;issue=1;spage=1;epage=4;aulast=Nayyar;type=0