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ORIGINAL ARTICLE
Year : 2017  |  Volume : 6  |  Issue : 1  |  Page : 1-4

Cytomorphometric analysis of exfoliated buccal mucosal cells in smokers and tobacco chewers


1 Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani, India
2 Department of Oral Medicine and Radiology, Pandit Deendayal Upadhyay Dental College and Hospital, Solapur, Maharashtra, India

Correspondence Address:
Abhishek Singh Nayyar
Department of Oral Medicine and Radiology, Saraswati Dhanwantari Dental College and Hospital, Post-Graduate Research Institute, Parbhani - 431 401, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijhi.ijhi_4_17

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Aims and Objectives: Exfoliative cytology is a minimally invasive procedure that has been used for the detection of early changes in clinically normal oral mucosa of tobacco users. This study highlights the cause-effect relationship between tobacco usage in varied forms and the structural cellular and nuclear alterations in different age groups. Materials and Methods: This study was conducted with different age groups who were tobacco users as a planned, cross-sectional study. Results: The results of the study revealed that the mean nuclear diameter (ND) and cytoplasmic diameter (CD) showed a statistically significant difference in the control group and in smokers and tobacco chewers. Conclusion: Increase in ND and decreased CD, as well as an altered nucleo-cytoplasmic ratio, appear to be due to chronic tobacco usage and cytomorphometric analysis can be used to detect these cellular and subcellular alterations at an early enough stage before actually a frank, morphological change can be appreciated in relation to the oral mucosa.


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